EMD-21147

Single-particle
3.3 Å
EMD-21147
3D View Gallery
Deposition: 20/12/2019
Map released: 22/07/2020
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-21147

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-6vcb summary report (pdf.gz) Map-6vcb FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Cryo-EM structure of the Glucagon-like peptide-1 receptor in complex with G protein, GLP-1 peptide and a positive allosteric modulator

EMD-21147

Single-particle
3.3 Å
EMD-21147
3D View Gallery
Deposition: 20/12/2019
Map released: 22/07/2020
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: Cryo-EM structure of the Glucagon-like peptide-1 receptor in complex with G protein, GLP-1 peptide and a positive allosteric modulator
Fitted models: 6vcb

Deposition Authors: Sun B , Feng D
Structural insights into probe-dependent positive allosterism of the GLP-1 receptor.
Bueno AB, Sun B , Willard FS , Feng D, Ho JD, Wainscott DB, Showalter AD, Vieth M, Chen Q , Stutsman C, Chau B, Ficorilli J, Agejas FJ, Cumming GR , Jimenez A, Rojo I, Kobilka TS, Kobilka BK , Sloop KW
(2020) Nat Chem Biol , 16 , 1105 - 1110
PUBMED: 32690941
DOI: doi:10.1038/s41589-020-0589-7
ISSN: 1552-4469