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EMD-20863

Single-particle
3.87 Å
EMD-20863
3D View Gallery
Deposition: 26/10/2019
Map released: 29/04/2020
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-20863
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 6usf summary report (pdf.gz) Map and 6usf FULL report (pdf.gz)
EMICSS annotations (xml)

CryoEM structure of human alpha4beta2 nicotinic acetylcholine receptor with varenicline in complex with anti-BRIL synthetic antibody BAK5

EMD-20863

Single-particle
3.87 Å
EMD-20863
3D View Gallery
Deposition: 26/10/2019
Map released: 29/04/2020
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: human alpha4beta2 nicotinic acetylcholine receptor in complex fab fragments and bound to varenicline
Fitted models: 6usf

Deposition Authors: Alvarez FJD, Mukherjee S, Han S
Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins.
Mukherjee S, Erramilli SK , Ammirati M, Alvarez FJD, Fennell KF, Purdy MD, Skrobek BM , Radziwon K, Coukos J , Kang Y, Dutka P , Gao X, Qiu X, Yeager M, Eric Xu H, Han S , Kossiakoff AA
(2020) Nat Commun , 11 , 1598 - 1598
PUBMED: 32221310
DOI: doi:10.1038/s41467-020-15363-0
ISSN: 2041-1723