EMD-20834

Single-particle
4.02 Å
EMD-20834
3D View Gallery
Deposition: 15/10/2019
Map released: 15/01/2020
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-20834

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-6uox summary report (pdf.gz) Map-6uox FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Structure of itraconazole-bound NPC1

EMD-20834

Single-particle
4.02 Å
EMD-20834
3D View Gallery
Deposition: 15/10/2019
Map released: 15/01/2020
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: NPC1 and itraconazole-Br complex
Fitted models: 6uox

Deposition Authors: Long T , Li X
Structural basis for itraconazole-mediated NPC1 inhibition.
Long T , Qi X, Hassan A , Liang Q, De Brabander JK, Li X
(2020) Nat Commun , 11 , 152 - 152
PUBMED: 31919352
DOI: doi:10.1038/s41467-019-13917-5
ISSN: 2041-1723