EMD-20523

Single-particle
3.1 Å
EMD-20523
3D View Gallery
Deposition: 28/07/2019
Map released: 04/09/2019
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-20523
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 6pxw summary report (pdf.gz) Map and 6pxw FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of full-length insulin receptor bound to 4 insulin. 3D refinement was focused on the top part of the receptor complex.

EMD-20523

Single-particle
3.1 Å
EMD-20523
3D View Gallery
Deposition: 28/07/2019
Map released: 04/09/2019
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Full-length insulin receptor/insulin complex
Fitted models: 6pxw

Deposition Authors: Uchikawa E , Choi E
Activation mechanism of the insulin receptor revealed by cryo-EM structure of the fully liganded receptor-ligand complex.
Uchikawa E , Choi E , Shang G , Yu H , Bai XC
(2019) eLife , 8
PUBMED: 31436533
DOI: doi:10.7554/eLife.48630
ISSN: 2050-084X