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EMD-20483
Structure of HIV cleaved synaptic complex (CSC) intasome bound with magnesium and Bictegravir (BIC)
EMD-20483
Single-particle2.9 Å
Deposition: 18/07/2019Map released: 12/02/2020
Last modified: 20/03/2024
Sample Organism:
Human immunodeficiency virus 1,
hiv
Sample: Assembly of HIV integrase and viral DNA
Fitted models: 6puw
Deposition Authors: Lyumkis D
,
Passos D
Sample: Assembly of HIV integrase and viral DNA
Fitted models: 6puw
Deposition Authors: Lyumkis D
,
Passos D
Structural basis for strand-transfer inhibitor binding to HIV intasomes.
Passos DO
,
Li M,
Jozwik IK
,
Zhao XZ
,
Santos-Martins D
,
Yang R
,
Smith SJ,
Jeon Y
,
Forli S
,
Hughes SH,
Burke Jr TR
,
Craigie R
,
Lyumkis D
(2020) Science , 367 , 810 - 814
,
Li M,
Jozwik IK
,
Zhao XZ
,
Santos-Martins D
,
Yang R
,
Smith SJ,
Jeon Y
,
Forli S
,
Hughes SH,
Burke Jr TR
,
Craigie R
,
Lyumkis D
(2020) Science , 367 , 810 - 814
Grant Support:
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): R01 AI136680 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): GM069832 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): R01 AI146017 (United States)
