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EMD-20470
Cryo-EM structure of human cannabinoid receptor 2-Gi protein in complex with agonist WIN 55,212-2
EMD-20470
Single-particle3.2 Å
Deposition: 14/07/2019Map released: 12/02/2020
Last modified: 28/05/2025
Sample Organism:
Homo sapiens,
synthetic construct
Sample: human cannabinoid receptor 2-Gi protein
Fitted models: 6pt0
Deposition Authors: Xu TH, Xing C
Sample: human cannabinoid receptor 2-Gi protein
Fitted models: 6pt0
Deposition Authors: Xu TH, Xing C
Cryo-EM Structure of the Human Cannabinoid Receptor CB2-GiSignaling Complex.
Xing C,
Zhuang Y
,
Xu TH,
Feng Z
,
Zhou XE,
Chen M
,
Wang L,
Meng X,
Xue Y,
Wang J,
Liu H,
McGuire TF,
Zhao G,
Melcher K
,
Zhang C
,
Xu HE,
Xie XQ
(2020) Cell , 180 , 645
,
Xu TH,
Feng Z
,
Zhou XE,
Chen M
,
Wang L,
Meng X,
Xue Y,
Wang J,
Liu H,
McGuire TF,
Zhao G,
Melcher K
,
Zhang C
,
Xu HE,
Xie XQ
(2020) Cell , 180 , 645
Grant Support:
- National Institutes of Health/National Institute on Drug Abuse (NIH/NIDA): P30 DA035778A1 (United States)
- National Institutes of Health/National Institute on Drug Abuse (NIH/NIDA): R01 DA025612 (United States)
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): 1R35GM128641 (United States)
- Ministry of Science and Technology (MoST, China): XDB08020303 (China)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): 1R01GM127710 (United States)
- Jay and Betty Van Andel Foundation: (United States)
