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EMD-20277
CRF1 Receptor Gs GPCR protein complex with CRF1 peptide.
EMD-20277
Single-particle2.91 Å
Deposition: 10/06/2019Map released: 05/02/2020
Last modified: 04/06/2025
Sample Organism:
Homo sapiens,
Lama glama
Sample: Complex of active-state Corticotropin-releasing hormone receptor 1 with heterotrimeric Gs protein.
Fitted models: 6p9x
Deposition Authors: Belousoff MJ
,
Liang YL
Sample: Complex of active-state Corticotropin-releasing hormone receptor 1 with heterotrimeric Gs protein.
Fitted models: 6p9x
Deposition Authors: Belousoff MJ
,
Liang YL
Toward a Structural Understanding of Class B GPCR Peptide Binding and Activation.
Liang YL,
Belousoff MJ ,
Zhao P,
Koole C,
Fletcher MM ,
Truong TT,
Julita V,
Christopoulos G,
Xu HE ,
Zhang Y ,
Khoshouei M,
Christopoulos A,
Danev R,
Sexton PM,
Wootten D
(2020) Mol Cell , 77 , 656 - 668.e5
,
Zhao P,
Koole C,
Fletcher MM ,
Truong TT,
Julita V,
Christopoulos G,
Xu HE ,
Zhang Y ,
Khoshouei M,
Christopoulos A,
Danev R,
Sexton PM,
Wootten D
(2020) Mol Cell , 77 , 656 - 668.e5
Grant Support:
- National Health and Medical Research Council (Australia): 1120919 (Australia)
- National Health and Medical Research Council (Australia): 1159006 (Australia)
- National Health and Medical Research Council (Australia): 1150083 (Australia)
- Japan Society for the Promotion of Science: KAKENHI #18H06043 (Japan)
- Japan Science and Technology: PRESTO #18069571 (Japan)