EMD-20179
Non-peptide agonist (TT-OAD2) bound to the Glucagon-Like peptide-1 (GLP-1) Receptor
EMD-20179
Single-particle3.0 Å
Deposition: 01/05/2019Map released: 08/01/2020
Last modified: 16/10/2024
Sample Organism:
Homo sapiens
Sample: TT-OAD2:GLP-1R:Gs Complex
Fitted models: 6orv
Deposition Authors: Belousoff MJ
,
Liang YL
Sample: TT-OAD2:GLP-1R:Gs Complex
Fitted models: 6orv
Deposition Authors: Belousoff MJ
,
Liang YL
Activation of the GLP-1 receptor by a non-peptidic agonist.
Zhao P,
Liang YL,
Belousoff MJ ,
Deganutti G ,
Fletcher MM ,
Willard FS,
Bell MG,
Christe ME,
Sloop KW,
Inoue A,
Truong TT,
Clydesdale L,
Furness SGB,
Christopoulos A,
Wang MW,
Miller LJ,
Reynolds CA ,
Danev R,
Sexton PM,
Wootten D
(2020) Nature , 577 , 432 - 436
,
Deganutti G ,
Fletcher MM ,
Willard FS,
Bell MG,
Christe ME,
Sloop KW,
Inoue A,
Truong TT,
Clydesdale L,
Furness SGB,
Christopoulos A,
Wang MW,
Miller LJ,
Reynolds CA ,
Danev R,
Sexton PM,
Wootten D
(2020) Nature , 577 , 432 - 436
Grant Support:
- National Health and Medical Research Council (NHMRC, Australia): 1061044 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): 1065410 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): 1120919 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): 1126857 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): 1055134 (Australia)