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EMD-20179

Single-particle
3.0 Å
EMD-20179
3D View Gallery
Deposition: 01/05/2019
Map released: 08/01/2020
Last modified: 16/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-20179
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 6orv summary report (pdf.gz) Map and 6orv FULL report (pdf.gz)
EMICSS annotations (xml)

Non-peptide agonist (TT-OAD2) bound to the Glucagon-Like peptide-1 (GLP-1) Receptor

EMD-20179

Single-particle
3.0 Å
EMD-20179
3D View Gallery
Deposition: 01/05/2019
Map released: 08/01/2020
Last modified: 16/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: TT-OAD2:GLP-1R:Gs Complex
Fitted models: 6orv

Deposition Authors: Belousoff MJ , Liang YL
Activation of the GLP-1 receptor by a non-peptidic agonist.
Zhao P, Liang YL, Belousoff MJ , Deganutti G , Fletcher MM , Willard FS, Bell MG, Christe ME, Sloop KW, Inoue A, Truong TT, Clydesdale L, Furness SGB, Christopoulos A, Wang MW, Miller LJ, Reynolds CA , Danev R, Sexton PM, Wootten D
(2020) Nature , 577 , 432 - 436
PUBMED: 31915381
DOI: doi:10.1038/s41586-019-1902-z
ISSN: 1476-4687
ASTM: NATUAS