EMD-19852

Helical reconstruction
2.3 Å
EMD-19852
3D View Gallery
Deposition: 14/03/2024
Map released: 10/07/2024
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-19852

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9eoe summary report (pdf.gz) Map-9eoe FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

PHF type tau filament from V337M mutant

EMD-19852

Helical reconstruction
2.3 Å
EMD-19852
3D View Gallery
Deposition: 14/03/2024
Map released: 10/07/2024
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: TF tau filament from mutant V337M
Fitted models: 9eoe

Deposition Authors: Qi C, Scheres SHW , Michel G
Tau filaments with the Alzheimer fold in human MAPT mutants V337M and R406W.
Qi C, Lovestam S, Murzin AG, Peak-Chew S , Franco C , Bogdani M, Latimer C, Murrell JR, Cullinane PW, Jaunmuktane Z, Bird TD, Ghetti B , Scheres SHW , Goedert M
(2025) Nat Struct Mol Biol , 32 , 1297 - 1304
PUBMED: 40044789
DOI: doi:10.1038/s41594-025-01498-5
ISSN: 1545-9985