Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-19740

Helical reconstruction
4.0 Å
EMD-19740
3D View Gallery
Deposition: 23/02/2024
Map released: 17/04/2024
Last modified: 17/04/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-19740
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8s5m summary report (pdf.gz) Map and 8s5m FULL report (pdf.gz)
EMICSS annotations (xml)

Full-length human cystathionine beta-synthase with C-terminal 6xHis-tag, SAM bound, activated state, helical reconstruction

EMD-19740

Helical reconstruction
4.0 Å
EMD-19740
3D View Gallery
Deposition: 23/02/2024
Map released: 17/04/2024
Last modified: 17/04/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Helical assembly of full-length human cystathionine beta-synthase in the basal state
Fitted models: 8s5m

Deposition Authors: McCorvie TJ , Yue WW
Architecture and regulation of filamentous human cystathionine beta-synthase.
McCorvie TJ , Adamoski D , Machado RAC , Tang J, Bailey HJ, Ferreira DSM, Strain-Damerell C , Basle A, Ambrosio ALB , Dias SMG , Yue WW
(2024) Nat Commun , 15 , 2931 - 2931
PUBMED: 38575566
DOI: doi:10.1038/s41467-024-46864-x
ISSN: 2041-1723
Grant Support: