EMD-19605

Single-particle
3.37 Å
EMD-19605
3D View Gallery
Deposition: 12/02/2024
Map released: 13/11/2024
Last modified: 27/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-19605

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8rz7 summary report (pdf.gz) Map-8rz7 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

(CAG)2 DNA-bound MutSbeta in open form with kinked MSH2 clamp

EMD-19605

Single-particle
3.37 Å
EMD-19605
3D View Gallery
Deposition: 12/02/2024
Map released: 13/11/2024
Last modified: 27/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: MutSbeta-DNA-ADP complex
Fitted models: 8rz7

Deposition Authors: Lee J-H, Thomsen M, Daub H, Steinbacher S, Sztyler A, Thieulin-Pardo G, Neudegger T, Plotnikov N, Iyer RR, Wilkinson H, Monteagudo E, Felsenfeld DP, Haque T, Finley M, Dominguez C, Vogt TF, Prasad BC
Elucidation of multiple high-resolution states of human MutS beta by cryo-EM reveals interplay between ATP/ADP binding and heteroduplex DNA recognition.
Lee JH, Thomsen M, Daub H, Thieulin-Pardo G, Steinbacher S, Sztyler A, Dahiya V, Neudegger T, Dominguez C, Iyer RR, Wilkinson HA, Monteagudo E, Plotnikov NV, Felsenfeld DP, Haque TS, Finley M, Boudet J, Vogt TF, Prasad BC
(2025) Nucleic Acids Res , 53
PUBMED: 40613711
DOI: doi:10.1093/nar/gkaf604
ISSN: 1362-4962
ASTM: NARHAD
Grant Support: