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EMD-19445
GPCR - G-protein complex
EMD-19445
Composite mapSingle-particle
3.03 Å
Deposition: 18/01/2024Map released: 27/11/2024
Last modified: 22/01/2025
Sample Organism:
Homo sapiens,
Mus musculoides
Sample: Human Taste receptor type 2 member 14 in complex with G-proteins
Fitted models: 8rql
Deposition Authors: Matzov D, Peri L
,
Niv M,
Shalev Benami M
Sample: Human Taste receptor type 2 member 14 in complex with G-proteins
Fitted models: 8rql
Deposition Authors: Matzov D, Peri L
,
Niv M,
Shalev Benami M
A bitter anti-inflammatory drug binds at two distinct sites of a human bitter taste GPCR.
Peri L ,
Matzov D,
Huxley DR ,
Rainish A,
Fierro F ,
Sapir L ,
Pfeiffer T ,
Waterloo L ,
Hubner H ,
Peleg Y,
Gmeiner P ,
McCormick PJ ,
Weikert D ,
Niv MY ,
Shalev-Benami M
(2024) Nat Commun , 15 , 9991 - 9991
,
Matzov D,
Huxley DR ,
Rainish A,
Fierro F ,
Sapir L ,
Pfeiffer T ,
Waterloo L ,
Hubner H ,
Peleg Y,
Gmeiner P ,
McCormick PJ ,
Weikert D ,
Niv MY ,
Shalev-Benami M
(2024) Nat Commun , 15 , 9991 - 9991
Grant Support:
- European Research Council (ERC): 949364 (European Union)