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EMD-19440
Cryo-EM structure of human NTCP-Bulevirtide complex
EMD-19440
Single-particle3.41 Å
Deposition: 18/01/2024Map released: 27/03/2024
Last modified: 23/10/2024
Sample Organism:
Homo sapiens,
Lama glama,
hepatitis B virus genotype C
Sample: Structure of Bulevirtide-bound human NTCP in complex with Fab and nanobody
Fitted models: 8rqf
Deposition Authors: Liu H
,
Zakrzewicz D,
Nosol K ,
Irobalieva RN ,
Mukherjee S ,
Bang-Soerensen R ,
Goldmann N,
Kunz S ,
Rossi L ,
Kossiakoff AA ,
Urban S ,
Glebe D ,
Geyer J ,
Locher KP
Sample: Structure of Bulevirtide-bound human NTCP in complex with Fab and nanobody
Fitted models: 8rqf
Deposition Authors: Liu H
,
Zakrzewicz D,
Nosol K ,
Irobalieva RN ,
Mukherjee S ,
Bang-Soerensen R ,
Goldmann N,
Kunz S ,
Rossi L ,
Kossiakoff AA ,
Urban S ,
Glebe D ,
Geyer J ,
Locher KP
Structure of antiviral drug bulevirtide bound to hepatitis B and D virus receptor protein NTCP.
Liu H ,
Zakrzewicz D,
Nosol K ,
Irobalieva RN ,
Mukherjee S ,
Bang-Sorensen R,
Goldmann N,
Kunz S ,
Rossi L ,
Kossiakoff AA ,
Urban S ,
Glebe D ,
Geyer J ,
Locher KP
(2024) Nat Commun , 15 , 2476 - 2476
,
Zakrzewicz D,
Nosol K ,
Irobalieva RN ,
Mukherjee S ,
Bang-Sorensen R,
Goldmann N,
Kunz S ,
Rossi L ,
Kossiakoff AA ,
Urban S ,
Glebe D ,
Geyer J ,
Locher KP
(2024) Nat Commun , 15 , 2476 - 2476
Grant Support:
- Swiss National Science Foundation: 214834 (Switzerland)
- Swiss National Science Foundation: 189111 (Switzerland)
- German Research Foundation (DFG): 197785619 (Germany)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): GM117372 (United States)