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EMD-19394

Single-particle
3.52 Å
EMD-19394
3D View Gallery
Deposition: 09/01/2024
Map released: 11/09/2024
Last modified: 11/09/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-19394
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8rnc summary report (pdf.gz) Map and 8rnc FULL report (pdf.gz)
EMICSS annotations (xml)

Influenza B polymerase, replication complex, an asymmetric polymerase dimer bound to human ANP32A (from "Influenza B polymerase apo-trimer" | Local refinement)

EMD-19394

Single-particle
3.52 Å
EMD-19394
3D View Gallery
Deposition: 09/01/2024
Map released: 11/09/2024
Last modified: 11/09/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Influenza B virus (B/Memphis/13/2003), Homo sapiens
Sample: Asymmetric dimer of two FluPolB heterotrimers, bridged by human ANP32A
Fitted models: 8rnc

Deposition Authors: Arragain B , Cusack S
Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase.
Arragain B , Krischuns T , Pelosse M , Drncova P, Blackledge M , Naffakh N , Cusack S
(2024) Nat Commun , 15 , 6910 - 6910
PUBMED: 39160148
DOI: doi:10.1038/s41467-024-51007-3
ISSN: 2041-1723