EMD-19341

Helical reconstruction
3.5 Å
EMD-19341
3D View Gallery
Deposition: 03/01/2024
Map released: 16/07/2025
Last modified: 18/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-19341

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8rlm summary report (pdf.gz) Map-8rlm FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

TRIF Oligomerisation

EMD-19341

Helical reconstruction
3.5 Å
EMD-19341
3D View Gallery
Deposition: 03/01/2024
Map released: 16/07/2025
Last modified: 18/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: TRIF TIR domain complex
Fitted models: 8rlm

Deposition Authors: Moncrieffe MC , Verstak B, Whitely L, Symmoms MF, Soares SG, Egelman EH , Klenerman D , Bryant CE , Gay NJ
Toll-like receptor signaling outcome is determined by the stoichiometry of the endogenous TRIFosome.
Moncrieffe MC , Suresh P , Boyle J , Cui Y , Nawalpuri B , Verstak B, Zhang YP, Zhang Z, Taylor M , Egelman EH , Gay N , Klenerman D , Bryant C
(2026) Sci Adv , 12 , eaeb9507 - eaeb9507
PUBMED: 41790885
DOI: doi:10.1126/sciadv.aeb9507
ISSN: 2375-2548