EMD-19195
Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in complex with Sec61-RAMP4
EMD-19195
Single-particle2.69243 Å
Deposition: 20/12/2023Map released: 24/01/2024
Last modified: 07/08/2024
Sample Organism:
Oryctolagus cuniculus,
Canis lupus familiaris,
Bos taurus,
Oryctolagus,
Sus scrofa
Sample: 80S ribosome translating a stalled, two-TMD nascent chain (derived from rhodopsin), and bound to Sec61, the TRAP complex, and RAMP4
Fitted models: 8rjb
Deposition Authors: Lewis AJO
,
Hegde RS
Sample: 80S ribosome translating a stalled, two-TMD nascent chain (derived from rhodopsin), and bound to Sec61, the TRAP complex, and RAMP4
Fitted models: 8rjb
Deposition Authors: Lewis AJO
,
Hegde RS
Structural analysis of the dynamic ribosome-translocon complex.
Secondary citations:
- Goddard TD, Huang CC, Meng EC, Pettersen EF, Couch GS, Morris JH & Ferrin TE. (2018) UCSF ChimeraX: Meeting modern challenges in visualization and analysis. 27, 14 - 25
- & Croll TI. (2018) ISOLDE: a physically realistic environment for model building into low-resolution electron-density maps. Acta Crystallogr D Struct Biol, 74, 519 - 530
- Kimanius D, Dong L, Sharov G, Nakane T & Scheres SHW. (2021) New tools for automated cryo-EM single-particle analysis in RELION-4.0. 478, 4169 - 4185
Grant Support:
- Medical Research Council (MRC, United Kingdom): MC_UP_A022_1007 (United Kingdom)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R01 GM130051 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R01 GM086487 (United States)
