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EMD-19186
Cryo-EM structure of the MCM double hexamer loaded onto dsDNA.
EMD-19186
Single-particle2.79 Å
Deposition: 18/12/2023Map released: 01/01/2025
Last modified: 01/10/2025
Sample Organism:
Saccharomyces cerevisiae
Sample: MCM-double hexamer loaded onto double-stranded DNA
Fitted models: 8rif
Deposition Authors: Miller TCR
,
Lim CT
,
Diffley JFX
,
Costa A
Sample: MCM-double hexamer loaded onto double-stranded DNA
Fitted models: 8rif
Deposition Authors: Miller TCR
,
Lim CT
,
Diffley JFX
,
Costa A
Cell cycle regulation has shaped replication origins in budding yeast.
Lim CT
,
Miller TCR
,
Tan KW
,
Talele S,
Early A
,
East P
,
Sanchez H,
Dekker NH
,
Costa A
,
Diffley JFX
(2025) Nat Struct Mol Biol , 32 , 1697 - 1707
,
Miller TCR
,
Tan KW
,
Talele S,
Early A
,
East P
,
Sanchez H,
Dekker NH
,
Costa A
,
Diffley JFX
(2025) Nat Struct Mol Biol , 32 , 1697 - 1707
Grant Support:
- Wellcome Trust: FC001065 (United Kingdom)
- Medical Research Council (MRC, United Kingdom): FC001065 (United Kingdom)
- Cancer Research UK: FC001065 (United Kingdom)
- European Research Council (ERC): 820102 (European Union)
- Novo Nordisk Foundation: NNF22OC0073571 (Denmark)
- Danish National Research Foundation: DNRF115 (Denmark)
