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EMD-19184
Late alpha-Synuclein fibril structure from liquid-liquid phase separations.
EMD-19184
Helical reconstruction3.3 Å
Deposition: 18/12/2023Map released: 06/03/2024
Last modified: 01/05/2024
Sample Organism:
Homo sapiens
Sample: Fibrillar complex of alpha-synuclein
Fitted models: 8ri9
Deposition Authors: De Simone A
,
Barritt JD ,
Chen S,
Cascella R ,
Cecchi C ,
Bigi A ,
Jarvis JA ,
Chiti F ,
Dobson CM,
Fusco G
Sample: Fibrillar complex of alpha-synuclein
Fitted models: 8ri9
Deposition Authors: De Simone A
,
Barritt JD ,
Chen S,
Cascella R ,
Cecchi C ,
Bigi A ,
Jarvis JA ,
Chiti F ,
Dobson CM,
Fusco G
Structure-Toxicity Relationship in Intermediate Fibrils from alpha-Synuclein Condensates.
Chen SW,
Barritt JD ,
Cascella R ,
Bigi A ,
Cecchi C ,
Banchelli M ,
Gallo A ,
Jarvis JA ,
Chiti F ,
Dobson CM,
Fusco G ,
De Simone A
(2024) J Am Chem Soc , 146 , 10537 - 10549
,
Cascella R ,
Bigi A ,
Cecchi C ,
Banchelli M ,
Gallo A ,
Jarvis JA ,
Chiti F ,
Dobson CM,
Fusco G ,
De Simone A
(2024) J Am Chem Soc , 146 , 10537 - 10549
Grant Support:
- European Research Council (ERC): 819644 (European Union)