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EMD-19176

Single-particle
3.0 Å
EMD-19176
3D View Gallery
Deposition: 15/12/2023
Map released: 20/11/2024
Last modified: 16/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-19176
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8rhh summary report (pdf.gz) Map and 8rhh FULL report (pdf.gz)
EMICSS annotations (xml)

Microtubule-associated kinesin-1 tail complex bound to AMPPNP, two-headed state

EMD-19176

Single-particle
3.0 Å
EMD-19176
3D View Gallery
Deposition: 15/12/2023
Map released: 20/11/2024
Last modified: 16/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Sus scrofa, Homo sapiens
Sample: 13pf microtubule bound to Kif5bMoNeIAK in the presence of AMPPNP (two-headed state)
Fitted models: 8rhh

Deposition Authors: Atherton J , Chegkazi MS, Steiner RA
Microtubule association induces a Mg-free apo-like ADP pre-release conformation in kinesin-1 that is unaffected by its autoinhibitory tail.
Atherton J , Chegkazi MS, Leusciatti M, Di Palma M , Peirano E , Pozzer LS , Meli MVA, Pasqualato S , Foran T, Morra G , Steiner RA
(2025) Nat Commun , 16 , 6214 - 6214
PUBMED: 40617823
DOI: doi:10.1038/s41467-025-61498-3
ISSN: 2041-1723