EMD-19110

Single-particle
2.98 Å
EMD-19110
3D View Gallery
Deposition: 12/12/2023
Map released: 26/03/2025
Last modified: 08/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-19110

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8rew summary report (pdf.gz) Map-8rew FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CryoEM structure of human GARP-lTGFbeta1 in complex with a Fab fragment derived from an activating antibody.

EMD-19110

Single-particle
2.98 Å
EMD-19110
3D View Gallery
Deposition: 12/12/2023
Map released: 26/03/2025
Last modified: 08/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: human GAPR-lTGFbeta1 in complex with Fab LHT-22.
Fitted models: 8rew

Deposition Authors: Felix J, Lambert F, Marien L, van der Woning B, Savvides SN, Lucas S
Antibody-mediated TGF-beta 1 activation for the treatment of diseases caused by deleterious T cell activity.
Lambert F, Felix J, Wautier S, Dupre E, Jamez M, Michiels C, Gaignage M, Marien L, Lesage M, van der Woning B, Savvides SN, Lucas S
(2025) Cell Rep , 44 , 116061 - 116061
PUBMED: 40742810
DOI: doi:10.1016/j.celrep.2025.116061
ISSN: 2211-1247