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EMD-19061
human TRPM4 in SMA IBA
EMD-19061
Single-particle3.5 Å
Deposition: 07/12/2023Map released: 18/12/2024
Last modified: 05/02/2025
Sample Organism:
Homo sapiens
Sample: homotetramer
Fitted models: 8rcu
Deposition Authors: Ekundayo B
,
Prakash A,
Christian G,
Anne FH,
Sabrina G,
Mey B,
Daniela R,
Martin L,
Jean SR,
Henning S,
Hugues A,
Dongchun N
Sample: homotetramer
Fitted models: 8rcu
Deposition Authors: Ekundayo B
,
Prakash A,
Christian G,
Anne FH,
Sabrina G,
Mey B,
Daniela R,
Martin L,
Jean SR,
Henning S,
Hugues A,
Dongchun N
Identification of a binding site for small molecule inhibitors targeting human TRPM4.
Ekundayo B ,
Arullampalam P,
Gerber CE ,
Hammerli AF,
Guichard S,
Boukenna M,
Ross-Kaschitza D ,
Lochner M ,
Rougier JS ,
Stahlberg H ,
Abriel H ,
Ni D
(2025) Nat Commun , 16 , 833 - 833
,
Arullampalam P,
Gerber CE ,
Hammerli AF,
Guichard S,
Boukenna M,
Ross-Kaschitza D ,
Lochner M ,
Rougier JS ,
Stahlberg H ,
Abriel H ,
Ni D
(2025) Nat Commun , 16 , 833 - 833
Grant Support:
- Swiss National Science Foundation: CRSII5_177195 (Switzerland)
- Swiss National Science Foundation: NCCR TransCure (185544) (Switzerland)