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EMD-18978
Cryo-EM structure of the human UAP56 - TREX-2 complex
EMD-18978
Single-particle3.5 Å
Deposition: 25/11/2023Map released: 11/06/2025
Last modified: 26/11/2025
Sample Organism:
Homo sapiens
Sample: Human UAP56 - TREX-2 complex
Fitted models: 8r7k
Deposition Authors: Hohmann U
,
Graf M ,
Plaschka C
Sample: Human UAP56 - TREX-2 complex
Fitted models: 8r7k
Deposition Authors: Hohmann U
,
Graf M ,
Plaschka C
An ATP-gated molecular switch orchestrates human messenger RNA export.
Hohmann U ,
Graf M ,
Tirian L,
Pacheco-Fiallos B ,
Schellhaas U ,
Fin L,
Handler D ,
Philipps AW,
Riabov-Bassat D,
Faraway RW ,
Puhringer T ,
Szalay MF ,
Roitinger E ,
Brennecke J ,
Plaschka C
(2025) Nature
,
Graf M ,
Tirian L,
Pacheco-Fiallos B ,
Schellhaas U ,
Fin L,
Handler D ,
Philipps AW,
Riabov-Bassat D,
Faraway RW ,
Puhringer T ,
Szalay MF ,
Roitinger E ,
Brennecke J ,
Plaschka C
(2025) Nature
Grant Support:
- European Research Council (ERC): 949081 (European Union)
- H2020 Marie Curie Actions of the European Commission: 896416 (European Union)
- European Molecular Biology Organization (EMBO): ALTF_1175-2019 (European Union)