EMD-18874

Helical reconstruction
3.1 Å
EMD-18874
3D View Gallery
Deposition: 10/11/2023
Map released: 06/12/2023
Last modified: 09/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-18874

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8r3t summary report (pdf.gz) Map-8r3t FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cofactor-free Tau 4R2N isoform

EMD-18874

Helical reconstruction
3.1 Å
EMD-18874
3D View Gallery
Deposition: 10/11/2023
Map released: 06/12/2023
Last modified: 09/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: In vitro assembled MAPT P-10636 4R2N isoform
Fitted models: 8r3t

Deposition Authors: Limorenko G, Tatli M , Kolla R, Nazarov S, Weil MT, Schondorf DC, Geist D, Reinhardt P, Ehrnhoefer DE, Stahlberg H , Gasparini L , Lashuel HA
Fully co-factor-free ClearTau platform produces seeding-competent Tau fibrils for reconstructing pathological Tau aggregates.
Limorenko G, Tatli M , Kolla R, Nazarov S, Weil MT, Schondorf DC, Geist D, Reinhardt P, Ehrnhoefer DE, Stahlberg H , Gasparini L , Lashuel HA
(2023) Nat Commun , 14 , 3939 - 3939
PUBMED: 37402718
DOI: doi:10.1038/s41467-023-39314-7
ISSN: 2041-1723
Grant Support: