EMD-18668

Single-particle
3.68 Å
EMD-18668
3D View Gallery
Deposition: 17/10/2023
Map released: 19/02/2025
Last modified: 19/02/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-18668
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8qv6 summary report (pdf.gz) Map and 8qv6 FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of human SPNS2 in DDM

EMD-18668

Single-particle
3.68 Å
EMD-18668
3D View Gallery
Deposition: 17/10/2023
Map released: 19/02/2025
Last modified: 19/02/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Vicugna pacos
Sample: Complex of SPNS2 with nanobody D12
Fitted models: 8qv6

Deposition Authors: Li HZ, Pike ACW , McKinley G, Mukhopadhyay SMM, Moreau C, Scacioc A, Abrusci P, Borkowska O, Chalk R, Stefanic S , Burgess-Brown N, Duerr KL, Sauer DB
Transport and inhibition of the sphingosine-1-phosphate exporter SPNS2.
Li HZ, Pike ACW , Chang YN, Prakaash D, Gelova Z, Stanka J , Moreau C, Scott HC, Wunder F , Wolf G , Scacioc A, McKinley G, Batoulis H, Mukhopadhyay S, Garofoli A, Pinto-Fernandez A , Kessler BM , Burgess-Brown NA, Stefanic S , Wiedmer T , Durr KL , Puetter V, Ehrmann A, Khalid S , Ingles-Prieto A, Superti-Furga G , Sauer DB
(2025) Nat Commun , 16 , 721 - 721
PUBMED: 39820269
DOI: doi:10.1038/s41467-025-55942-7
ISSN: 2041-1723
Grant Support: