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EMD-18595
Cryo-EM structure of the human inward-rectifier potassium 2.1 channel (Kir2.1) - R312H mutant
EMD-18595
Single-particle6.0 Å
Deposition: 05/10/2023Map released: 04/12/2024
Last modified: 04/12/2024
Sample Organism:
Homo sapiens
Sample: Human inward-rectifier potassium 2.1 channel (Kir2.1) containing the Andersen-syndrome related mutation R312H
Fitted models: 8qql
Deposition Authors: Fernandes CAH
,
Zuniga D ,
Venien-Bryan C
Sample: Human inward-rectifier potassium 2.1 channel (Kir2.1) containing the Andersen-syndrome related mutation R312H
Fitted models: 8qql
Deposition Authors: Fernandes CAH
,
Zuniga D ,
Venien-Bryan C
Biochemical, biophysical, and structural investigations of two mutants (C154Y and R312H) of the human Kir2.1 channel involved in the Andersen-Tawil syndrome.
Zuniga D ,
Zoumpoulakis A ,
Veloso RF,
Peverini L ,
Shi S,
Pozza A ,
Kugler V,
Bonnete F ,
Bouceba T,
Wagner R ,
Corringer PJ ,
Fernandes CAH ,
Venien-Bryan C
(2024) FASEB J , 38 , e70146 - e70146
,
Zoumpoulakis A ,
Veloso RF,
Peverini L ,
Shi S,
Pozza A ,
Kugler V,
Bonnete F ,
Bouceba T,
Wagner R ,
Corringer PJ ,
Fernandes CAH ,
Venien-Bryan C
(2024) FASEB J , 38 , e70146 - e70146
Grant Support:
- The French Muscular Dystrophy Telethon (AFM-Telethon): #23207 (France)
- H2020 Marie Curie Actions of the European Commission: 101026386 (European Union)