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EMD-18570

Helical reconstruction
2.5 Å
EMD-18570
3D View Gallery
Deposition: 03/10/2023
Map released: 04/09/2024
Last modified: 04/09/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-18570
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8qpz summary report (pdf.gz) Map and 8qpz FULL report (pdf.gz)
EMICSS annotations (xml)

CryoEM structure of recombinant DeltaN7 alpha-synuclein in PBS

EMD-18570

Helical reconstruction
2.5 Å
EMD-18570
3D View Gallery
Deposition: 03/10/2023
Map released: 04/09/2024
Last modified: 04/09/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: alpha-synuclein DeltaN7 amyloid fibrils
Fitted models: 8qpz

Deposition Authors: Thacker D, Wilkinson M , Dewison KM , Ranson NA , Brockwell DJ , Radford SE
Residues 2 to 7 of alpha-synuclein regulate amyloid formation via lipid-dependent and lipid-independent pathways.
Dewison KM , Rowlinson B , Machin JM , Crossley JA , Thacker D, Wilkinson M , Ulamec SM, Khan GN , Ranson NA , van Oosten-Hawle P , Brockwell DJ , Radford SE
(2024) PNAS , 121 , e2315006121 - e2315006121
PUBMED: 39133842
DOI: doi:10.1073/pnas.2315006121
ISSN: 1091-6490
ASTM: PNASA6