EMD-18541
Structure of the mu opioid receptor bound to the antagonist nanobody NbE
EMD-18541
Single-particle3.2 Å
Deposition: 29/09/2023Map released: 27/12/2023
Last modified: 29/01/2025
Sample Organism:
Mus musculus,
Lama glama,
synthetic construct
Sample: MOR-NbE-NabFab-AntiFab complex
Fitted models: 8qot
Deposition Authors: Yu J
,
Kumar A ,
Zhang X ,
Martin C,
Raia P ,
Manglik A ,
Ballet S ,
Boland A ,
Stoeber M
Sample: MOR-NbE-NabFab-AntiFab complex
Fitted models: 8qot
Deposition Authors: Yu J
,
Kumar A ,
Zhang X ,
Martin C,
Raia P ,
Manglik A ,
Ballet S ,
Boland A ,
Stoeber M
Structural basis of mu-opioid receptor targeting by a nanobody antagonist.
Yu J ,
Kumar A ,
Zhang X ,
Martin C,
Van Holsbeeck K ,
Raia P ,
Koehl A,
Laeremans T,
Steyaert J ,
Manglik A ,
Ballet S ,
Boland A ,
Stoeber M
(2024) Nat Commun , 15 , 8687 - 8687
,
Kumar A ,
Zhang X ,
Martin C,
Van Holsbeeck K ,
Raia P ,
Koehl A,
Laeremans T,
Steyaert J ,
Manglik A ,
Ballet S ,
Boland A ,
Stoeber M
(2024) Nat Commun , 15 , 8687 - 8687
Grant Support:
- Swiss National Science Foundation: TMSGI3_211581 (Switzerland)
- Swiss National Science Foundation: 310030_185235 (Switzerland)
- Swiss National Science Foundation: PCEFP3_181282 (Switzerland)