Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-18269

Helical reconstruction
3.09 Å
EMD-18269
3D View Gallery
Deposition: 19/08/2023
Map released: 11/10/2023
Last modified: 18/10/2023
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-18269
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8q96 summary report (pdf.gz) Map and 8q96 FULL report (pdf.gz)
EMICSS annotations (xml)

P301S Tau Filaments from the Brains of Tg2541 Transgenic Mouse Line

EMD-18269

Helical reconstruction
3.09 Å
EMD-18269
3D View Gallery
Deposition: 19/08/2023
Map released: 11/10/2023
Last modified: 18/10/2023
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: P301S Tau Protein Filament (Tg2541)
Fitted models: 8q96

Deposition Authors: Schweighauser M, Murzin AG, Macdonald J, Lavenir I, Crowther RA, Scheres SHW, Goedert M
Cryo-EM structures of tau filaments from the brains of mice transgenic for human mutant P301S Tau.
Schweighauser M, Murzin AG, Macdonald J, Lavenir I, Crowther RA, Scheres SHW, Goedert M
(2023) Acta Neuropathol , 11 , 160 - 160
PUBMED: 37798679
DOI: doi:10.1186/s40478-023-01658-y
ISSN: 2051-5960