EMD-18249

Helical reconstruction
2.95 Å
EMD-18249
3D View Gallery
Deposition: 18/08/2023
Map released: 30/08/2023
Last modified: 24/01/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-18249

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8q88 summary report (pdf.gz) Map-8q88 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Tau - AD-LIA2 (tau intermediate amyloid)

EMD-18249

Helical reconstruction
2.95 Å
EMD-18249
3D View Gallery
Deposition: 18/08/2023
Map released: 30/08/2023
Last modified: 24/01/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Amyloid
Fitted models: 8q88

Deposition Authors: Lovestam S, Li D , Scheres SHW , Goedert M
Disease-specific tau filaments assemble via polymorphic intermediates.
Lovestam S, Li D , Wagstaff JL, Kotecha A , Kimanius D, McLaughlin SH , Murzin AG, Freund SMV , Goedert M , Scheres SHW
(2024) Nature , 625 , 119 - 125
PUBMED: 38030728
DOI: doi:10.1038/s41586-023-06788-w
ISSN: 1476-4687
ASTM: NATUAS
Grant Support: