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EMD-17805
MERS-CoV Nsp1 bound to the human 43S pre-initiation complex
EMD-17805
Single-particle2.65 Å
Deposition: 07/07/2023Map released: 18/10/2023
Last modified: 24/04/2024
Sample Organism:
Homo sapiens,
Middle East respiratory syndrome-related coronavirus
Sample: MERS-CoV Nsp1 - 43S pre-initiation complex
Fitted models: 8ppl
Deposition Authors: Schubert K, Karousis ED
,
Ban I,
Lapointe CP,
Leibundgut M,
Baeumlin E,
Kummerant E
,
Scaiola A,
Schoenhut T,
Ziegelmueller J,
Puglisi JD,
Muehlemann O,
Ban N
Sample: MERS-CoV Nsp1 - 43S pre-initiation complex
Fitted models: 8ppl
Deposition Authors: Schubert K, Karousis ED
,
Ban I,
Lapointe CP,
Leibundgut M,
Baeumlin E,
Kummerant E
,
Scaiola A,
Schoenhut T,
Ziegelmueller J,
Puglisi JD,
Muehlemann O,
Ban N
Universal features of Nsp1-mediated translational shutdown by coronaviruses.
Schubert K,
Karousis ED
,
Ban I,
Lapointe CP,
Leibundgut M,
Baumlin E,
Kummerant E
,
Scaiola A,
Schonhut T,
Ziegelmuller J,
Puglisi JD,
Muhlemann O,
Ban N
(2023) Mol Cell , 83 , 3546 - 3557.e8
,
Ban I,
Lapointe CP,
Leibundgut M,
Baumlin E,
Kummerant E
,
Scaiola A,
Schonhut T,
Ziegelmuller J,
Puglisi JD,
Muhlemann O,
Ban N
(2023) Mol Cell , 83 , 3546 - 3557.e8
Grant Support:
- Swiss National Science Foundation: 182341 (Switzerland)
- Swiss National Science Foundation: 182831 (Switzerland)
- Swiss National Science Foundation: 204161 (Switzerland)
- Swiss National Science Foundation: 51NF40-182880 (Switzerland)
- Swiss National Science Foundation: 51NF40--205601 (Switzerland)
- Other government: ETH-23 18-2 (Switzerland)
- Other government: (Switzerland)
- Other private: (Switzerland)
- Other private: (Switzerland)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): GM011378 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): GM145306 (United States)
- National Institutes of Health/National Institute on Aging (NIH/NIA): AG064690 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): K99GM144678 (United States)
