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EMD-17758
Human bile salt export pump (BSEP) in complex with inhibitor GBM in nanodiscs
EMD-17758
Single-particle3.22 Å
Deposition: 28/06/2023Map released: 22/11/2023
Last modified: 09/07/2025
Sample Organism:
Homo sapiens
Sample: The complex of BSEP with inhibitor GBM
Fitted models: 8pm6
Deposition Authors: Liu H
,
Irobalieva RN ,
Kowal J ,
Ni D ,
Nosol K ,
Bang-Sorensen R,
Lancien L,
Stahlberg H ,
Stieger B ,
Locher KP
Sample: The complex of BSEP with inhibitor GBM
Fitted models: 8pm6
Deposition Authors: Liu H
,
Irobalieva RN ,
Kowal J ,
Ni D ,
Nosol K ,
Bang-Sorensen R,
Lancien L,
Stahlberg H ,
Stieger B ,
Locher KP
Structural basis of bile salt extrusion and small-molecule inhibition in human BSEP.
Liu H ,
Irobalieva RN ,
Kowal J ,
Ni D ,
Nosol K ,
Bang-Sorensen R,
Lancien L,
Stahlberg H ,
Stieger B ,
Locher KP
(2023) Nat Commun , 14 , 7296 - 7296
,
Irobalieva RN ,
Kowal J ,
Ni D ,
Nosol K ,
Bang-Sorensen R,
Lancien L,
Stahlberg H ,
Stieger B ,
Locher KP
(2023) Nat Commun , 14 , 7296 - 7296
Grant Support:
- Swiss National Science Foundation: 189111 (Switzerland)
- Swiss National Science Foundation: 206089 (Switzerland)
- Swiss National Science Foundation: 185544 (Switzerland)