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EMD-17756
Structure of the murine trace amine-associated receptor TAAR7f bound to N,N-dimethylcyclohexylamine (DMCH) in complex with mini-Gs trimeric G protein
EMD-17756
Single-particle2.92 Å
Deposition: 28/06/2023Map released: 09/08/2023
Last modified: 09/07/2025
Sample Organism:
Homo sapiens,
Lama glama,
Mus musculus
Sample: A complex of mouse trace-amine associated receptor 7f solubilized in LMNG/CHS bound to N,N-dimethylcyclohexylamine and coupled to: Engineered guanine nucleotide-binding protein G(s) subunit alpha isoform short + Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 + Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 + Nanobody 35
Fitted models: 8pm2
Deposition Authors: Gusach A, Lee Y, Edwards PC, Huang F, Weyand SN, Tate CG
Sample: A complex of mouse trace-amine associated receptor 7f solubilized in LMNG/CHS bound to N,N-dimethylcyclohexylamine and coupled to: Engineered guanine nucleotide-binding protein G(s) subunit alpha isoform short + Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 + Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 + Nanobody 35
Fitted models: 8pm2
Deposition Authors: Gusach A, Lee Y, Edwards PC, Huang F, Weyand SN, Tate CG
Molecular recognition of an aversive odorant by the murine trace amine-associated receptor TAAR7f.
Gusach A,
Lee Y,
Khoshgrudi AN,
Mukhaleva E,
Ma N,
Koers EJ
,
Chen Q,
Edwards PC,
Huang F,
Kim J,
Mancia F,
Verprintsev DB,
Vaidehi N,
Weyand SN,
Tate CG
(2023) bioRxiv
,
Chen Q,
Edwards PC,
Huang F,
Kim J,
Mancia F,
Verprintsev DB,
Vaidehi N,
Weyand SN,
Tate CG
(2023) bioRxiv
Grant Support:
- Medical Research Council (MRC, United Kingdom): MC_U105197215 (United Kingdom)
