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EMD-17630
ABCB1 L335C mutant (mABCB1) in the inward facing state bound to AAC
EMD-17630
Single-particle3.8 Å
Deposition: 13/06/2023Map released: 20/03/2024
Last modified: 13/11/2024
Sample Organism:
Mus musculus
Sample: ABCB1
Fitted models: 8pee
Deposition Authors: Parey K
,
Januliene D ,
Gewering T,
Moeller A ,
Vecchis D,
Striednig B,
Hilbi H,
Schaefer LV,
Kuprov I,
Bordignon E,
Seeger MA,
Moeller A
Sample: ABCB1
Fitted models: 8pee
Deposition Authors: Parey K
,
Januliene D ,
Gewering T,
Moeller A ,
Vecchis D,
Striednig B,
Hilbi H,
Schaefer LV,
Kuprov I,
Bordignon E,
Seeger MA,
Moeller A
Tracing the substrate translocation mechanism in P-glycoprotein.
Gewering T,
Waghray D,
Parey K ,
Jung H ,
Tran NNB,
Zapata J,
Zhao P,
Chen H ,
Januliene D ,
Hummer G ,
Urbatsch I ,
Moeller A ,
Zhang Q
(2024) eLife , 12
,
Jung H ,
Tran NNB,
Zapata J,
Zhao P,
Chen H ,
Januliene D ,
Hummer G ,
Urbatsch I ,
Moeller A ,
Zhang Q
(2024) eLife , 12
Grant Support:
- German Research Foundation (DFG): CRC944 (Germany)
- German Research Foundation (DFG): INST 190-196-1 FUGG (Germany)