Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-17542
Negative stain map of UBR5 (dimer) in complex with RARA/RXRA
EMD-17542
Single-particle25.0 Å
Deposition: 31/05/2023Map released: 07/06/2023
Last modified: 27/12/2023
Sample Organism:
Homo sapiens
Sample: UBR5 in complex with RARA/RXRA
Deposition Authors: Aguirre JD
,
Cavadini S,
Kempf G,
Kater L,
Thoma NH
Sample: UBR5 in complex with RARA/RXRA
Deposition Authors: Aguirre JD
,
Cavadini S,
Kempf G,
Kater L,
Thoma NH
UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability.
Tsai JM,
Aguirre JD ,
Li YD ,
Brown J,
Focht V,
Kater L,
Kempf G,
Sandoval B,
Schmitt S,
Rutter JC,
Galli P,
Sandate CR ,
Cutler JA ,
Zou C,
Donovan KA,
Lumpkin RJ,
Cavadini S,
Park PMC,
Sievers Q,
Hatton C,
Ener E,
Regalado BD ,
Sperling MT,
Slabicki M,
Kim J,
Zon R,
Zhang Z,
Miller PG,
Belizaire R,
Sperling AS,
Fischer ES,
Irizarry R,
Armstrong SA,
Thoma NH ,
Ebert BL
(2023) Mol Cell , 83 , 2753 - 2767.e10
,
Li YD ,
Brown J,
Focht V,
Kater L,
Kempf G,
Sandoval B,
Schmitt S,
Rutter JC,
Galli P,
Sandate CR ,
Cutler JA ,
Zou C,
Donovan KA,
Lumpkin RJ,
Cavadini S,
Park PMC,
Sievers Q,
Hatton C,
Ener E,
Regalado BD ,
Sperling MT,
Slabicki M,
Kim J,
Zon R,
Zhang Z,
Miller PG,
Belizaire R,
Sperling AS,
Fischer ES,
Irizarry R,
Armstrong SA,
Thoma NH ,
Ebert BL
(2023) Mol Cell , 83 , 2753 - 2767.e10
Grant Support:
- Swiss National Science Foundation: 179541 (Switzerland)
- Swiss National Science Foundation: 201206 (Switzerland)
- European Research Council (ERC): 884331 (European Union)