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EMD-17539
Cryo-EM structure of dimeric UBR5
EMD-17539
Single-particle3.36 Å
Deposition: 31/05/2023Map released: 14/06/2023
Last modified: 26/06/2024
Sample Organism:
Homo sapiens
Sample: Dimer of UBR5
Fitted models: 8p82
Deposition Authors: Aguirre JD
,
Kater L,
Kempf G,
Cavadini S,
Thoma NH
Sample: Dimer of UBR5
Fitted models: 8p82
Deposition Authors: Aguirre JD
,
Kater L,
Kempf G,
Cavadini S,
Thoma NH
UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability.
Tsai JM,
Aguirre JD ,
Li YD ,
Brown J,
Focht V,
Kater L,
Kempf G,
Sandoval B,
Schmitt S,
Rutter JC,
Galli P,
Sandate CR ,
Cutler JA ,
Zou C,
Donovan KA,
Lumpkin RJ,
Cavadini S,
Park PMC,
Sievers Q,
Hatton C,
Ener E,
Regalado BD ,
Sperling MT,
Slabicki M,
Kim J,
Zon R,
Zhang Z,
Miller PG,
Belizaire R,
Sperling AS,
Fischer ES,
Irizarry R,
Armstrong SA,
Thoma NH ,
Ebert BL
(2023) Mol Cell , 83 , 2753 - 2767.e10
,
Li YD ,
Brown J,
Focht V,
Kater L,
Kempf G,
Sandoval B,
Schmitt S,
Rutter JC,
Galli P,
Sandate CR ,
Cutler JA ,
Zou C,
Donovan KA,
Lumpkin RJ,
Cavadini S,
Park PMC,
Sievers Q,
Hatton C,
Ener E,
Regalado BD ,
Sperling MT,
Slabicki M,
Kim J,
Zon R,
Zhang Z,
Miller PG,
Belizaire R,
Sperling AS,
Fischer ES,
Irizarry R,
Armstrong SA,
Thoma NH ,
Ebert BL
(2023) Mol Cell , 83 , 2753 - 2767.e10
Grant Support:
- Swiss National Science Foundation: 179541 (Switzerland)
- Swiss National Science Foundation: 201206 (Switzerland)
- European Research Council (ERC): 884331 (European Union)