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EMD-17362
Homotypic interacting B1 fab bound to Chondroitin Sulfate A
EMD-17362
Single-particle3.2 Å
Deposition: 16/05/2023Map released: 05/06/2024
Last modified: 02/07/2025
Sample Organism:
Homo sapiens
Sample: B1 fabs bound to chondroitin sulphate A
Fitted models: 8p2e
Deposition Authors: Raghavan SSR
,
Dagil R ,
Wang KT,
Salanti A
Sample: B1 fabs bound to chondroitin sulphate A
Fitted models: 8p2e
Deposition Authors: Raghavan SSR
,
Dagil R ,
Wang KT,
Salanti A
Tumor-agnostic cancer therapy using antibodies targeting oncofetal chondroitin sulfate.
Vidal-Calvo EE ,
Martin-Salazar A ,
Choudhary S ,
Dagil R ,
Raghavan SSR ,
Duvnjak L,
Nordmaj MA ,
Clausen TM,
Skafte A ,
Oberkofler J,
Wang K ,
Agerbaek MO ,
Loppke C ,
Jorgensen AM ,
Ropac D,
Mujollari J,
Willis S,
Garcias Lopez A,
Miller RL ,
Karlsson RTG ,
Goerdeler F ,
Chen YH ,
Colaco AR,
Wang Y ,
Lavstsen T ,
Martowicz A,
Nelepcu I ,
Marzban M,
Oo HZ ,
Orum-Madsen MS ,
Wang Y ,
Nielsen MA ,
Clausen H ,
Wierer M,
Wolf D,
Gogenur I,
Theander TG ,
Al-Nakouzi N ,
Gustavsson T,
Daugaard M ,
Salanti A
(2024) Nat Commun , 15 , 7553 - 7553
,
Martin-Salazar A ,
Choudhary S ,
Dagil R ,
Raghavan SSR ,
Duvnjak L,
Nordmaj MA ,
Clausen TM,
Skafte A ,
Oberkofler J,
Wang K ,
Agerbaek MO ,
Loppke C ,
Jorgensen AM ,
Ropac D,
Mujollari J,
Willis S,
Garcias Lopez A,
Miller RL ,
Karlsson RTG ,
Goerdeler F ,
Chen YH ,
Colaco AR,
Wang Y ,
Lavstsen T ,
Martowicz A,
Nelepcu I ,
Marzban M,
Oo HZ ,
Orum-Madsen MS ,
Wang Y ,
Nielsen MA ,
Clausen H ,
Wierer M,
Wolf D,
Gogenur I,
Theander TG ,
Al-Nakouzi N ,
Gustavsson T,
Daugaard M ,
Salanti A
(2024) Nat Commun , 15 , 7553 - 7553
Grant Support:
- Novo Nordisk Foundation: NNF22OC0076055 (Denmark)
- Novo Nordisk Foundation: NNF21OC0068192 (Denmark)
- The Carlsberg Foundation: CF20-0045 (Denmark)