Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-17296
Stabilised BA.1 SARS-CoV-2 spike with H6 nanobodies in '2 up 1 down' RBD conformation
EMD-17296
Single-particle4.0 Å
Deposition: 05/05/2023Map released: 15/05/2024
Last modified: 16/10/2024
Sample Organism:
Lama glama,
Severe acute respiratory syndrome coronavirus 2,
Enterobacteria phage T4
Sample: Complex of stabilised HexaPro Omicron BA.1 spike trimer with two H6 nanobodies
Fitted models: 8oyu
Deposition Authors: Weckener M, Naismith JH, Owens RJ
Sample: Complex of stabilised HexaPro Omicron BA.1 spike trimer with two H6 nanobodies
Fitted models: 8oyu
Deposition Authors: Weckener M, Naismith JH, Owens RJ
Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-2.
Cornish K,
Huo J,
Jones L,
Sharma P,
Thrush JW ,
Abdelkarim S,
Kipar A,
Ramadurai S,
Weckener M,
Mikolajek H,
Liu S,
Buckle I ,
Bentley E ,
Kirby A,
Han X,
Laidlaw SM,
Hill M,
Eyssen L,
Norman C,
Le Bas A ,
Clarke J ,
James W ,
Stewart JP ,
Carroll M,
Naismith JH,
Owens RJ
(2024) Open Biol , 14 , 230252 - 230252
,
Abdelkarim S,
Kipar A,
Ramadurai S,
Weckener M,
Mikolajek H,
Liu S,
Buckle I ,
Bentley E ,
Kirby A,
Han X,
Laidlaw SM,
Hill M,
Eyssen L,
Norman C,
Le Bas A ,
Clarke J ,
James W ,
Stewart JP ,
Carroll M,
Naismith JH,
Owens RJ
(2024) Open Biol , 14 , 230252 - 230252
Grant Support:
- Wellcome Trust: 223733/Z/21/Z (United Kingdom)