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EMD-17156
Cryo-EM structure of CLOCK-BMAL1 bound to a nucleosomal E-box at position SHL-6.2 (DNA conformation 2)
EMD-17156
Single-particle3.8 Å
Deposition: 19/04/2023Map released: 24/05/2023
Last modified: 26/07/2023
Sample Organism:
Homo sapiens,
synthetic construct,
Mus musculus
Sample: CLOCK-BMAL1 bound to a nucleosome at SHL -6.2
Deposition Authors: Michael AK
,
Stoos L,
Kempf G,
Cavadini S,
Thoma NH
Sample: CLOCK-BMAL1 bound to a nucleosome at SHL -6.2
Deposition Authors: Michael AK
,
Stoos L,
Kempf G,
Cavadini S,
Thoma NH
Cooperation between bHLH transcription factors and histones for DNA access.
Michael AK ,
Stoos L,
Crosby P,
Eggers N ,
Nie XY ,
Makasheva K ,
Minnich M ,
Healy KL,
Weiss J ,
Kempf G,
Cavadini S,
Kater L,
Seebacher J,
Vecchia L,
Chakraborty D ,
Isbel L ,
Grand RS,
Andersch F ,
Fribourgh JL,
Schubeler D,
Zuber J ,
Liu AC ,
Becker PB ,
Fierz B ,
Partch CL ,
Menet JS ,
Thoma NH
(2023) Nature , 619 , 385 - 393
,
Stoos L,
Crosby P,
Eggers N ,
Nie XY ,
Makasheva K ,
Minnich M ,
Healy KL,
Weiss J ,
Kempf G,
Cavadini S,
Kater L,
Seebacher J,
Vecchia L,
Chakraborty D ,
Isbel L ,
Grand RS,
Andersch F ,
Fribourgh JL,
Schubeler D,
Zuber J ,
Liu AC ,
Becker PB ,
Fierz B ,
Partch CL ,
Menet JS ,
Thoma NH
(2023) Nature , 619 , 385 - 393
Grant Support:
- European Research Council (ERC): 884331 (European Union)
- Swiss National Science Foundation: CRSII5_186230 (Switzerland)
- Swiss National Science Foundation: 31003A_179541 (Switzerland)
- Swiss National Science Foundation: 310030_201206 (Switzerland)
- Human Frontier Science Program (HFSP): LT000646/2018-L5 (France)