EMD-17127
Cryo-EM structure of human tRNA ligase RTCB in complex with human PYROXD1.
EMD-17127
Single-particle3.3 Å
Deposition: 14/04/2023Map released: 30/10/2024
Last modified: 07/05/2025
Sample Organism:
Homo sapiens
Sample: Cryo-EM structure of human RTCB in complex with human PYROXD1.
Fitted models: 8orj
Deposition Authors: Loeff L, Kroupova A, Asanovic I
,
Boneberg F,
Pfleiderer MM ,
Ferdigg A ,
Ackle F ,
Martinez J ,
Jinek M
Sample: Cryo-EM structure of human RTCB in complex with human PYROXD1.
Fitted models: 8orj
Deposition Authors: Loeff L, Kroupova A, Asanovic I
,
Boneberg F,
Pfleiderer MM ,
Ferdigg A ,
Ackle F ,
Martinez J ,
Jinek M
Mechanistic basis for PYROXD1-mediated protection of the human tRNA ligase complex against oxidative inactivation.
Loeff L,
Kroupova A,
Asanovic I ,
Boneberg FM,
Pfleiderer MM ,
Riermeier L ,
Leitner A ,
Ferdigg A ,
Ackle F ,
Martinez J ,
Jinek M
(2025) Nat Struct Mol Biol
,
Boneberg FM,
Pfleiderer MM ,
Riermeier L ,
Leitner A ,
Ferdigg A ,
Ackle F ,
Martinez J ,
Jinek M
(2025) Nat Struct Mol Biol
Grant Support:
- Swiss National Science Foundation: 31003A_182567 (Switzerland)