Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-17117

Single-particle
3.8 Å
EMD-17117
3D View Gallery
Deposition: 13/04/2023
Map released: 28/06/2023
Last modified: 09/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-17117
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8or4 summary report (pdf.gz) Map and 8or4 FULL report (pdf.gz)
EMICSS annotations (xml)

Partially dissociated CAND1-CUL1-RBX1-SKP1-SKP2-CKS1-CDK2

EMD-17117

Single-particle
3.8 Å
EMD-17117
3D View Gallery
Deposition: 13/04/2023
Map released: 28/06/2023
Last modified: 09/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Partially dissociated CAND1-CUL1-RBX1-SKP1-SKP2-CKS1-CDK2
Fitted models: 8or4

Deposition Authors: Shaaban M , Clapperton JA, Ding S , Maeots ME, Enchev RI, Maslen SL, Skehel JM, Enchev RI
Structural and mechanistic insights into the CAND1-mediated SCF substrate receptor exchange.
Shaaban M , Clapperton JA, Ding S , Kunzelmann S, Maeots ME, Maslen SL, Skehel JM, Enchev RI
(2023) Mol Cell , 83 , 2332
PUBMED: 37339624
DOI: doi:10.1016/j.molcel.2023.05.034
ISSN: 1097-2765
ASTM: MOCEFL
Grant Support: