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EMD-17113

Single-particle
3.4 Å
EMD-17113
3D View Gallery
Deposition: 12/04/2023
Map released: 24/04/2024
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-17113
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8oqz summary report (pdf.gz) Map and 8oqz FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of human gamma-secretase PSEN1 APH-1B isoform reconstituted into lipid nanodisc in complex with Ab46

EMD-17113

Single-particle
3.4 Å
EMD-17113
3D View Gallery
Deposition: 12/04/2023
Map released: 24/04/2024
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Gamma secretase
Fitted models: 8oqz

Deposition Authors: Odorcic I , Chavez Gutierrez L, Efremov RG
Apo and A beta 46-bound gamma-secretase structures provide insights into amyloid-beta processing by the APH-1B isoform.
Odorcic I , Hamed MB , Lismont S, Chavez-Gutierrez L, Efremov RG
(2024) Nat Commun , 15 , 4479 - 4479
PUBMED: 38802343
DOI: doi:10.1038/s41467-024-48776-2
ISSN: 2041-1723