EMD-16957
DI2 Abeta fibril from tg-SwDI mouse
EMD-16957
Helical reconstruction4.2 Å
Deposition: 30/03/2023Map released: 29/11/2023
Last modified: 13/12/2023
Sample Organism:
Homo sapiens
Sample: Amyloid fibril of amyloid-beta
Fitted models: 8olg
Deposition Authors: Zielinski M
,
Peralta Reyes FS ,
Gremer L ,
Schemmert S,
Frieg B ,
Willuweit A ,
Donner L,
Elvers M,
Nilsson LNG ,
Syvanen S ,
Sehlin D ,
Ingelsson M,
Willbold D ,
Schroeder GF
Sample: Amyloid fibril of amyloid-beta
Fitted models: 8olg
Deposition Authors: Zielinski M
,
Peralta Reyes FS ,
Gremer L ,
Schemmert S,
Frieg B ,
Willuweit A ,
Donner L,
Elvers M,
Nilsson LNG ,
Syvanen S ,
Sehlin D ,
Ingelsson M,
Willbold D ,
Schroeder GF
Cryo-EM of A beta fibrils from mouse models find tg-APP ArcSwe fibrils resemble those found in patients with sporadic Alzheimer's disease.
Zielinski M ,
Peralta Reyes FS ,
Gremer L ,
Schemmert S,
Frieg B ,
Schafer LU ,
Willuweit A ,
Donner L,
Elvers M,
Nilsson LNG ,
Syvanen S ,
Sehlin D ,
Ingelsson M,
Willbold D ,
Schroder GF
(2023) Nat Neurosci , 26 , 2073 - 2080
,
Peralta Reyes FS ,
Gremer L ,
Schemmert S,
Frieg B ,
Schafer LU ,
Willuweit A ,
Donner L,
Elvers M,
Nilsson LNG ,
Syvanen S ,
Sehlin D ,
Ingelsson M,
Willbold D ,
Schroder GF
(2023) Nat Neurosci , 26 , 2073 - 2080
Grant Support:
- German Federal Ministry for Education and Research: 16LW028 (Germany)
- Swedish Research Council: 2021-02793 (Sweden)
- Swedish Research Council: 2021-01083 (Sweden)
- Swedish Research Council: 2021-03524 (Sweden)
- Helmholtz Association: (Germany)