Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-16876
Structure of the Tau-PAM4 Type 1 amyloid fibril
EMD-16876
Helical reconstruction2.6 Å
Deposition: 20/03/2023Map released: 21/02/2024
Last modified: 13/11/2024
Sample Organism:
synthetic construct
Sample: 2PF amyloid fibril assembly of Tau-PAM4 peptide
Fitted models: 8oh2
Deposition Authors: Wilkinson M
,
Louros N ,
Tsaka G,
Ramakers M ,
Morelli C ,
Garcia T,
Gallardo RU,
D'Haeyer S ,
Goossens V,
Audenaert D,
Thal DR ,
Ranson NA ,
Radford SE ,
Rousseau F ,
Schymkowitz J
Sample: 2PF amyloid fibril assembly of Tau-PAM4 peptide
Fitted models: 8oh2
Deposition Authors: Wilkinson M
,
Louros N ,
Tsaka G,
Ramakers M ,
Morelli C ,
Garcia T,
Gallardo RU,
D'Haeyer S ,
Goossens V,
Audenaert D,
Thal DR ,
Ranson NA ,
Radford SE ,
Rousseau F ,
Schymkowitz J
Local structural preferences in shaping tau amyloid polymorphism.
Louros N ,
Wilkinson M ,
Tsaka G,
Ramakers M ,
Morelli C ,
Garcia T,
Gallardo R,
D'Haeyer S ,
Goossens V,
Audenaert D,
Thal DR ,
Mackenzie IR,
Rademakers R ,
Ranson NA ,
Radford SE ,
Rousseau F ,
Schymkowitz J
(2024) Nat Commun , 15 , 1028 - 1028
,
Wilkinson M ,
Tsaka G,
Ramakers M ,
Morelli C ,
Garcia T,
Gallardo R,
D'Haeyer S ,
Goossens V,
Audenaert D,
Thal DR ,
Mackenzie IR,
Rademakers R ,
Ranson NA ,
Radford SE ,
Rousseau F ,
Schymkowitz J
(2024) Nat Commun , 15 , 1028 - 1028
Grant Support:
- Research Foundation - Flanders (FWO): (Belgium)