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EMD-16860

Single-particle
3.6 Å
EMD-16860
3D View Gallery
Deposition: 15/03/2023
Map released: 14/08/2024
Last modified: 14/08/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-16860
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8ofi summary report (pdf.gz) Map and 8ofi FULL report (pdf.gz)
EMICSS annotations (xml)

Ivabradine bound to HCN4 channel

EMD-16860

Single-particle
3.6 Å
EMD-16860
3D View Gallery
Deposition: 15/03/2023
Map released: 14/08/2024
Last modified: 14/08/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Oryctolagus cuniculus
Sample: HCN4
Fitted models: 8ofi

Deposition Authors: Saponaro A , Chaves-Sanjuan A , Sharifzadeh AS , Clarke OB , Marabelli C, Bolognesi M , Thiel G , Moroni A
Structural determinants of ivabradine block of the open pore of HCN4.
Saponaro A , Krumbach JH, Chaves-Sanjuan A , Sharifzadeh AS , Porro A , Castelli R , Hamacher K, Bolognesi M , DiFrancesco D , Clarke OB , Thiel G , Moroni A
(2024) PNAS , 121 , e2402259121 - e2402259121
PUBMED: 38917012
DOI: doi:10.1073/pnas.2402259121
ISSN: 1091-6490
ASTM: PNASA6