EMD-16665

Single-particle
2.8 Å
EMD-16665
3D View Gallery
Deposition: 08/02/2023
Map released: 11/10/2023
Last modified: 11/10/2023
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-16665
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8ci1 summary report (pdf.gz) Map and 8ci1 FULL report (pdf.gz)
EMICSS annotations (xml)

Human alpha7 nicotinic receptor in complex with the E3 nanobody and nicotine

EMD-16665

Single-particle
2.8 Å
EMD-16665
3D View Gallery
Deposition: 08/02/2023
Map released: 11/10/2023
Last modified: 11/10/2023
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens, Vicugna pacos
Sample: complex of the human alpha7 nicotinic acetylcholine receptor with the nanobody E3
Fitted models: 8ci1

Deposition Authors: Prevost MS , Barilone N, Dejean de la Batie G, Pons S, Ayme G , England P , Gielen M , Bontems F, Pehau-Arnaudet G , Maskos U, Lafaye P, Corringer P-J
An original potentiating mechanism revealed by the cryo-EM structures of the human alpha 7 nicotinic receptor in complex with nanobodies.
Prevost MS , Barilone N, Dejean de la Batie G, Pons S, Ayme G , England P , Gielen M , Bontems F, Pehau-Arnaudet G , Maskos U, Lafaye P, Corringer PJ
(2023) Nat Commun , 14 , 5964 - 5964
PUBMED: 37749098
DOI: doi:10.1038/s41467-023-41734-4
ISSN: 2041-1723