Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-16600
Type1 alpha-synuclein filament assembled in vitro by wild-type and mutant (7 residues insertion) protein
EMD-16600
Helical reconstruction2.7 Å
Deposition: 01/02/2023Map released: 01/03/2023
Last modified: 24/07/2024
Sample Organism:
Homo sapiens
Sample: Alpha-synuclein filament assembled in vitro by wild-type and mutant (7 residues insertion) protein
Fitted models: 8ce7
Deposition Authors: Yang Y
,
Garringer JH,
Shi Y,
Lovestam S,
Sew PC,
Zhang XJ,
Kotecha A ,
Bacioglu M,
Koto A,
Takao M,
Spillantini GM,
Ghetti B,
Vidal R ,
Murzin GA,
Scheres HWS,
Goedert M
Sample: Alpha-synuclein filament assembled in vitro by wild-type and mutant (7 residues insertion) protein
Fitted models: 8ce7
Deposition Authors: Yang Y
,
Garringer JH,
Shi Y,
Lovestam S,
Sew PC,
Zhang XJ,
Kotecha A ,
Bacioglu M,
Koto A,
Takao M,
Spillantini GM,
Ghetti B,
Vidal R ,
Murzin GA,
Scheres HWS,
Goedert M
New SNCA mutation and structures of alpha-synuclein filaments from juvenile-onset synucleinopathy.
Yang Y ,
Garringer HJ ,
Shi Y,
Lovestam S,
Peak-Chew S,
Zhang X,
Kotecha A ,
Bacioglu M,
Koto A,
Takao M,
Spillantini MG,
Ghetti B,
Vidal R ,
Murzin AG,
Scheres SHW,
Goedert M
(2023) Acta Neuropathol , 145 , 561 - 572
,
Garringer HJ ,
Shi Y,
Lovestam S,
Peak-Chew S,
Zhang X,
Kotecha A ,
Bacioglu M,
Koto A,
Takao M,
Spillantini MG,
Ghetti B,
Vidal R ,
Murzin AG,
Scheres SHW,
Goedert M
(2023) Acta Neuropathol , 145 , 561 - 572
Grant Support:
- Medical Research Council (MRC, United Kingdom): MC_UP_A025-1013 (United Kingdom)
- Medical Research Council (MRC, United Kingdom): MC_U105184291 (United Kingdom)