Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-16549

Single-particle
4.0 Å
EMD-16549
3D View Gallery
Deposition: 25/01/2023
Map released: 06/09/2023
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-16549
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8cbq summary report (pdf.gz) Map and 8cbq FULL report (pdf.gz)
EMICSS annotations (xml)

structure of LEDGF/p75 PWWP domain bound to the H3K36 trimethylated dinucleosome

EMD-16549

Single-particle
4.0 Å
EMD-16549
3D View Gallery
Deposition: 25/01/2023
Map released: 06/09/2023
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Xenopus laevis, synthetic construct, Homo sapiens
Sample: H3K36me3 dinucleosome-LEDGF/p75 PWWP domain complex
Fitted models: 8cbq

Deposition Authors: Koutna E , Kouba T , Novacek J , Veverka V
Multivalency of nucleosome recognition by LEDGF.
Koutna E , Lux V , Kouba T , Skerlova J , Novacek J , Srb P , Hexnerova R , Svachova H , Kukacka Z , Novak P , Fabry M, Poepsel S , Veverka V
(2023) Nucleic Acids Res , 51 , 10011 - 10025
PUBMED: 37615563
DOI: doi:10.1093/nar/gkad674
ISSN: 1362-4962
ASTM: NARHAD