EMD-16512
MiniCoV-ADDomer, a SARS-CoV-2 epitope presenting viral like particle
EMD-16512
Single-particle2.36 Å
Deposition: 23/01/2023Map released: 06/12/2023
Last modified: 20/12/2023
Sample Organism:
Human adenovirus B3
Sample: ADDomer Mini-COVID viral like particle vaccine derived from Human Ad3 penton base protein.
Fitted models: 8c9n
Deposition Authors: Bufton JC, Capin J, Boruku U, Garzoni F, Schaffitzel C, Berger I
Sample: ADDomer Mini-COVID viral like particle vaccine derived from Human Ad3 penton base protein.
Fitted models: 8c9n
Deposition Authors: Bufton JC, Capin J, Boruku U, Garzoni F, Schaffitzel C, Berger I
In vitro generated antibodies guide thermostable ADDomer nanoparticle design for nasal vaccination and passive immunization against SARS-CoV-2.
Buzas D,
Bunzel AH,
Staufer O,
Milodowski EJ,
Edmunds GL
,
Bufton JC,
Vidana Mateo BV,
Yadav SKN,
Gupta K
,
Fletcher C,
Williamson MK,
Harrison A,
Borucu U,
Capin J,
Francis O,
Balchin G,
Hall S,
Vega MV,
Durbesson F,
Lingappa S,
Vincentelli R,
Roe J,
Wooldridge L
,
Burt R,
Anderson RJL
,
Mulholland AJ
,
Hare J,
Bailey M
,
Davidson AD,
Finn A,
Morgan D
,
Mann J,
Spatz J
,
Garzoni F,
Schaffitzel C,
Berger I
(2023) Antib Ther , 6 , 277 - 297
,
Bufton JC,
Vidana Mateo BV,
Yadav SKN,
Gupta K
,
Fletcher C,
Williamson MK,
Harrison A,
Borucu U,
Capin J,
Francis O,
Balchin G,
Hall S,
Vega MV,
Durbesson F,
Lingappa S,
Vincentelli R,
Roe J,
Wooldridge L
,
Burt R,
Anderson RJL
,
Mulholland AJ
,
Hare J,
Bailey M
,
Davidson AD,
Finn A,
Morgan D
,
Mann J,
Spatz J
,
Garzoni F,
Schaffitzel C,
Berger I
(2023) Antib Ther , 6 , 277 - 297
Grant Support:
- Engineering and Physical Sciences Research Council: EP/R511663/1 (United Kingdom)
- Biotechnology and Biological Sciences Research Council (BBSRC): BB/L01386X/1 (United Kingdom)
- Wellcome Trust: 202904/Z/16/Z (United Kingdom)
- Wellcome Trust: 206181/Z/17/Z (United Kingdom)
- Biotechnology and Biological Sciences Research Council (BBSRC): BB/R000484/1 (United Kingdom)
- Engineering and Physical Sciences Research Council: EP/R013764/1 (United Kingdom)
- Wellcome Trust: 210701/Z/18/Z (United Kingdom)
- Wellcome Trust: 106115/Z/14/Z (United Kingdom)
