Electron Microscopy Data Bank

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EMD-16345

Single-particle
3.24 Å

3D View Gallery

Deposition: 15/12/2022
Map released: 22/03/2023
Last modified: 02/07/2025

Overview 3D View Sample Experiment Validation Additional data Links

EMD-16345

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Structure of SLC40/ferroportin in complex with vamifeport and synthetic nanobody Sy3 in occluded conformation

EMD-16345

Single-particle
3.24 Å
EMD-16345

3D View Gallery

Deposition: 15/12/2022
Map released: 22/03/2023
Last modified: 02/07/2025

Overview 3D View Sample Experiment Validation Additional data Links

Sample Organism: Homo sapiens, synthetic construct
Sample: Complex of ferroportin with synthetic nanobody and inhibitor
Fitted models: 8bzy

Deposition Authors: Lehmann EF , Liziczai M , Drozdzyk K , Dutzler R , Manatschal C

Structures of ferroportin in complex with its specific inhibitor vamifeport.

Lehmann EF , Liziczai M , Drozdzyk K , Altermatt P, Langini C, Manolova V, Sundstrom H, Durrenberger F , Dutzler R , Manatschal C
(2023) eLife , 12

PUBMED: 36943194
DOI: doi:10.7554/eLife.83053
ISSN: 2050-084X

Grant Support:

Swiss National Science Foundation: (Switzerland)