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EMD-16112
Human Urea Transporter UT-B/UT1 in Complex with Inhibitor UTBinh-14
EMD-16112
Single-particle2.6 Å
Deposition: 10/11/2022Map released: 04/10/2023
Last modified: 11/10/2023
Sample Organism:
Homo sapiens
Sample: Homotrimeric complex of Human Urea Transporter UT-B
Fitted models: 8blp
Deposition Authors: Chi G
,
Dietz L ,
Pike ACW ,
Maclean EM,
Mukhopadhyay SMM,
Bohstedt T,
Wang D ,
Scacioc A,
McKinley G,
Arrowsmith CH,
Edwards A,
Bountra C,
Fernandez-Cid A,
Burgess-Brown NA,
Duerr KL
Sample: Homotrimeric complex of Human Urea Transporter UT-B
Fitted models: 8blp
Deposition Authors: Chi G
,
Dietz L ,
Pike ACW ,
Maclean EM,
Mukhopadhyay SMM,
Bohstedt T,
Wang D ,
Scacioc A,
McKinley G,
Arrowsmith CH,
Edwards A,
Bountra C,
Fernandez-Cid A,
Burgess-Brown NA,
Duerr KL
Structural characterization of human urea transporters UT-A and UT-B and their inhibition.
Chi G ,
Dietz L ,
Tang H ,
Snee M ,
Scacioc A,
Wang D ,
Mckinley G ,
Mukhopadhyay SMM,
Pike ACW ,
Chalk R,
Burgess-Brown NA,
Timmermans JP ,
van Putte W,
Robinson CV ,
Durr KL
(2023) Sci Adv , 9 , eadg8229 - eadg8229
,
Dietz L ,
Tang H ,
Snee M ,
Scacioc A,
Wang D ,
Mckinley G ,
Mukhopadhyay SMM,
Pike ACW ,
Chalk R,
Burgess-Brown NA,
Timmermans JP ,
van Putte W,
Robinson CV ,
Durr KL
(2023) Sci Adv , 9 , eadg8229 - eadg8229
Grant Support:
- Wellcome Trust: 106169/Z//14/Z (United Kingdom)